lemborexant, ketamine. Either boosts effects of the opposite by sedation. Modify Therapy/Observe Carefully. Dosage adjustment could possibly be required if lemborexant is coadministered with other CNS depressants because of potentially additive outcomes.
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Reserve concomitant prescribing of such prescription drugs in patients for whom other treatment possibilities are inadequate. Limit dosages and durations for the bare minimum essential. Watch carefully for indications of respiratory melancholy and sedation.
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Monitor Closely (two)lemborexant will minimize the extent or influence of ketamine by impacting hepatic enzyme CYP2B6 metabolism.
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